| Date | Location | Result | |
| Dec 03, 2005 | Boone, N.C. | Appalachian State 38, Southern Illinois 24 | Box score |
| Nov 26, 2005 | Charleston, Ill. | Southern Illinois 21, Eastern Illinois 6 | Box score |
| Nov 19, 2005 | Carbondale, Ill. | Southern Illinois 9, North Dakota State 0 | Box score |
| Nov 12, 2005 | Cedar Falls, Iowa | Northern Iowa 25, Southern Illinois 24 | Box score |
| Nov 05, 2005 | Carbondale, Ill. | Southern Illinois 31, Youngstown State 17 | Box score |
| Oct 27, 2005 | Bowling Green, Ky. | Southern Illinois 31, Western Kentucky 20 | Box score |
| Oct 22, 2005 | Terre Haute, Ind. | Southern Illinois 42, Indiana State 20 | Box score |
| Oct 15, 2005 | Carbondale, Ill. | Illinois State 61, Southern Illinois 35 | Box score |
| Oct 08, 2005 | Macomb, Ill. | Southern Illinois 34, Western Illinois 24 | Box score |
| Oct 01, 2005 | Carbondale, Ill. | Southern Illinois 30, Missouri State 23 | Box score |
| Sep 17, 2005 | Kalamazoo,MI | Western Michigan 34, Southern Illinois 28 | Box score |
| Sep 10, 2005 | Carbondale, Ill. | Southern Illinois 82, UNION 7 | Box score |
| Sep 01, 2005 | Cape Girardeau, Mo. | Southern Illinois 58, SEMO 23 | Box score |